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Voriconazole is an antimycotic, or antifungal, drug. It kills infection-causing fungi or inhibits their growth. The drug is also active against fungi-like yeasts, such as Candida. Voriconazole is used to treat severe yeast and fungal infections, such as the lung infection aspergillosis or Candida infections.

Voriconazole and the benefit of DNA analysis

The rate at which voriconazole is processed within your body varies from one individual to another. This means that the efficacy and side effects of voriconazole can be predicted to some extent on the basis of your genes. Preventive DNA analysis can therefore be an important tool in optimising your medication.

Voriconazole and the enzyme CYP2C19

Voriconazole is processed within the body primarily by the enzyme CYP2C19. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of voriconazole can also differ from person to person.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with voriconazole.

Read more about CYP2C19 enzyme »

Also known as

Vfend, VCZ, Voriconazolum
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