Simvastatin and the transport protein SLCO1B1
Simvastatin is transported within the body (from the blood to the liver) primarily by the transport protein SLCO1B1. The activity of this transport protein can vary considerably depending on your genetic predisposition, which means the extent and nature of potential side effects can differ from person to person.
Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with simvastatin.
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