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Pimozide is a typical antipsychotic that is still frequently used. It inhibits the effects of dopamine, a naturally occurring substance, in the brain. Pimozide is prescribed to treat psychosis, schizophrenia and tics.

Pimozide and the benefit of DNA analysis

The rate at which pimozide is processed within your body varies from one individual to another. This means that the efficacy and side effects of pimozide can be predicted to some extent on the basis of your genes. Preventive DNA analysis can therefore be an important tool in optimising your medication.

Pimozide and the enzyme CYP2D6

Pimozide is processed to a large extent by the enzyme CYP2D6. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of pimozide can also differ from person to person.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with pimozide.

Read more about CYP2D6 enzyme »
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