Mercaptopurine and the enzyme TPMT
Mercaptopurine is processed to a large extent by the enzyme TPMT and NUDT15. The activity of these enzymes can vary considerably depending on your genetic predisposition, which means the efficacy of mercaptopurine can also differ from person to person.
Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with mercaptopurine.
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