Irinotecan and the enzyme UGT1A1
Irinotecan is processed to a large extent by the enzyme UGT1A1.
The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of irinotecan can also differ from person to person.
Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with irinotecan.
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