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Clomipramine (CYP2D6)

Clomipramine is an antidepressant forming part of the class of drugs known as tricyclic antidepressants (TCAs). TCAs inhibit the reuptake of the neurotransmitters serotonin and noradrenaline in the brain. They are older, but effective, drugs that are less selective than more modern reuptake inhibitors, such as SSRIs. Clomipramine is prescribed to treat depression, anxiety disorders and narcolepsy (uncontrollable sleep attacks).

Clomipramine and the benefit of DNA analysis

The rate at which clomipramine is processed within your body varies from one individual to another. This means that the efficacy and side effects of clomipramine can be predicted to some extent on the basis of your genes. Preventive DNA analysis can therefore be an important tool in optimising your medication.

Also known as

Chlorimipramine, Clomipramina, Clomipraminum, Monochlorimipramine, Anapramine, Hydiphen, Anafranil
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